Marijuana use is associated with decreased incidence of liver cirrhosis in those with the Hepatitis C Virus, according to a new study published by the Canadian Journal of Gastroenterology and Hepatology.
“The effect of cannabis use on chronic liver disease (CLD) from Hepatitis C Virus (HCV) infection, the most common cause of CLD, has been controversial”, states the study’s abstract. “Here, we investigated the impact of cannabis use on the prevalence of CLD among HCV infected individuals.”
For the study researchers “analyzed hospital discharge records of adults (age ≥ 18 years) with a positive HCV diagnosis”, evaluating “records from 2007 to 2014 of the Nationwide Inpatient Sample (NIS)” while excluding “records with other causes of chronic liver diseases (alcohol, hemochromatosis, NAFLD, PBC, HBV, etc.).”
Of the 188,333 records, researchers “matched cannabis users to nonusers on 1:1 ratio, using a propensity-based matching system, with a stringent algorithm.” They then “used conditional regression models with generalized estimating equations to measure the adjusted prevalence rate ratio (aPRR) for having liver cirrhosis (and its complications), carcinoma, mortality, discharge disposition, and the adjusted mean ratio (aMR) of total hospital cost and length of stay (LOS) [SAS 9.4].”
The study “revealed